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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2fa38126cbddc170add29559d933ea59e7a06a2c49c3de2627051083ef7cf74' 
  AND token = '+Q/8axy7siCDEnZ7MInS1eRjxoPDQgxMK5WH2hVpDqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}