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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ec0f1adb5666810b733d28faf609cb137fa36796b74ec0905a2b6c4f6fdf332' 
  AND token = 'U7te+qr6XrS8In/CiwsCtn+WFQu26hk6T8m1eu0GIaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}