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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '885ef872b6cfc505fe4a774902fbc26bfb1093e4efa101a11fb8ddbaa05398ad' 
  AND token = 'igs3k+vj2/qHxsq1qXOdS6dcI45lGHJP0M71Vpm1lEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}