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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ff220cfa06e10d4295c286063f3f200e9b8d241e588f504053fc2d97ba2a635' 
  AND token = 'Qh+ONeu6hjYHpgoyJ5nCfYPMeF95BhwReDrsfX+bBAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}