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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e2165e79f88041f4196f49a16eb232d0da25a471d6878e79e46a196c44130b' 
  AND token = '0/VeqKo5Pu699431c8CSINjYnDe7cvD31E72vhS0V94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}