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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce3d8e044f0d90c93fad25697e94a96a79a3cb6ab3b23da445b8ebe3a970f658' 
  AND token = '33nPqWwZDrspSEiAua8NpO1Z8UeC17iwgu8ZYErvW9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}