SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7325fd8a3da6dd2a57b83dc5b1414468846eb2ae0f8ed276decfd815af50de3' 
  AND token = 'lCyO52q2zDPhtFgW6OSYjN62yDPEuRJKoxW3gP0GTxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}