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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '423b2a5e0db1142f3f698120552cfff606226d045151e6de4a14672546f12186' 
  AND token = 'T8WC/jHP5+hk5GHh1ZKI0Xh3LrRIwT4wGhOpu+GZ8G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}