SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dc896ad486b2cfc0a20b8ea50476c7498d27bf541fd2013705bf74614a5eec8' 
  AND token = 'KGSY0T0NLnx+cCdeZ/lRbNwqYEI13wSU+UDrdARmKDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}