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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c7743c6f7a2c3a758ace6d421d6841565253f2d9854942a2ed69c49d7e052e2' 
  AND token = 'Fyhh9ChQwMeb3DDdJrlhUbmEhWMneoKMZe3djs+GJsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}