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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4671983950f4d3b10d3629653b9f504c5e3aa08f61802f60d6b222ade933e8e' 
  AND token = 'F0YXOnoUn9bU56uD1b3mYuJotWQELKlPJAu+JPaWzP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}