SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e22936eefc69ee6e71338606eec5f6f05ba0d16dc5842727073f34cb9f26930' 
  AND token = 'CW9p3XqZnDaN/ArRJKtpzci9L5B9DaDTlQOMk65uoqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}