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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae4e1b6a6b898ff232c2e8b279f49f4a5ac2f405ef51eaddff3daf1632009d85' 
  AND token = 'wKUg5nRFgDSkH6oa5fV1drA30fiGmiD5efkPehJyjTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}