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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9074e30bec2b446292a277c7730ab8bd0aef1754281d220fd5d0b81e07e43ca' 
  AND token = 'SWAvkcjA9Fs8w9Fn12aJjP/o1GKcatodVxBA2E2dfQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}