SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7033b49c9d900c7db2ab78f7335ae996d4eb7dee976526092ae5b6b3fdab33ac' 
  AND token = '4ORkAD2bpNZQxG7LHr1In3sD9ZvTV73kynua6ibADhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}