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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b28c1c3c99ce01b260735253878cc2d2fa5e135583dfb77047e6f1f761106b2' 
  AND token = 'JSbMq2YTTon7kUpBIUY2yOc+/J48lbIj6alVu41I+ZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}