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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '188a4c10d7d817256ebdc7773e9a58575e9ed0c048e79ae38123f120645d7074' 
  AND token = 'SgpPeL3Vb5dEetX9mdE2K8sxf6KczwJwaazeMTpa5xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}