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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ab1cd18ae6da4351d5735f479e5a3854db850edc5694744def92f8bd3bfb4d' 
  AND token = 'axOXtxETP1SKoRF81g/f90cSzEW2oGIrzH856Ym8aCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}