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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b88af7549f80a270a16d4f8d5b7b745a325c1f42ab6b97c76dbb5d68c298f440' 
  AND token = 'bkJ2c+dYpCl3Q2wjxky3NN2vgymvlU+37Y8lZIWckFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}