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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1308a02a52783d5cdb8e9e6c85d216a69b7c0e6cf38c5931996be0120d2be559' 
  AND token = '/eMJOdBUsO7AEWvFfgJdP4co1HoO2Ne7AUD6sEiCTq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}