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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b1880fb0486f8ac06f474127222f42c8bbdc37b597574e702f72fb2dfa33de6' 
  AND token = 'fjAqy9vawfccAAE8l2rVC2+0g238/VSrsLig2sDNzmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}