SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9fc8fac4cea158bb93875795c771d66fc9f141d696727f64c2b6bfae8fdb370' 
  AND token = 'CFhkiDVpnGiPoG6+sKca9+J9fv4pa9bTJgD5fTzk8Ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}