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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '404faf0b18b19255ec01502ce951df2a9b42b64f6ca70a1a90fdd1bd3ecb8d6a' 
  AND token = 'AaesXCAmNKUyQdZyXMZb/IDh2rYfMW7gxRiREvilP1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}