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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d638063d8b048f2d23c2fcd3235776677f2cd74760ae25866551b9c0dfe6ef5' 
  AND token = 'LWqzkLswkHsWmuhYlO7Bg7uw8qtQPyi+zDH2ksdhvaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}