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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '957ce22e12790c75bcd597c220442b6d85b8a29009f394a2fb5d82e7c8d0c706' 
  AND token = 'beEkqN4i6kwhrsM0ZsYcfmVTs4V5SOJngOSHyZL8SxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}