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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11f53420a5e1a810d481a58ced69714a2048a18f443fe53cacd4465b69bb5c58' 
  AND token = 'vEXDfrBrf7LxBD8MlsTAwGn3qQGHWC3WwjDJYMJsYiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}