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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b6dd1ee24d125568eb9be561e0f3ab413221769d3aa4a9f11cecccc0b11342f' 
  AND token = 'fJ0Ao+9ATRYGm5+rAT7sX8h/0sy/H5gtn+IwpESYu2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}