SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09e975a763fece347e0c9b9ad0b2c6a336765610c8e2237997a5a6a52f96d0c8' 
  AND token = 'AmdS8+4qX+L4OOSgqju1kWkT4evMwS7zXuvBiGwF6no=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}