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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd31a0ade212bb757258a3122241384111e5337849975a70b0d211542dc4178c' 
  AND token = 'NcUuEsf8kSL//fXykMOWnWBiyhNO6uDdb7w9Gr8GP5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}