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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '070f16888acd6ba6e7c442f741b0ad99b9c6f1a7578645dc13aa8643af5f0f6c' 
  AND token = 'GWxderMo+z+6BuS61c6URyUR/eWlJswumbui9DMUws4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}