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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15a679a8721b6fe9c7cf3fd33c083ed2f42e4af9ac71e373a53469e1185b41b7' 
  AND token = 'eFUgHSgN9qHwU6EV62LwuZFYc0sqouULk3aYwy3VsoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}