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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d95cd0c8895571bc51894f377a29a6b0baf155b923400e78f115e513a118471' 
  AND token = 'pXsFb/xYEMvq5h9Hhfe7bXlhNCTQuocgiWK4+DeKkcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}