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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45562a3fe3cd4d8d805b5473a445a0b163967525d5e1d9ab5df423247af607c5' 
  AND token = 'uo36CUfsZ74sZboB9awGwxsAg1pdFxN7NSA/TiYC9YI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}