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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e3d7260d7c134fcaf695a4730352014a47fd45687e197841e1d23b72a525dc5' 
  AND token = '/QgIu6W1aHNRxk2obb2icgMR7v/XG1jzi+xNHYkGKeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}