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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3db9cf872b08835c111d22aa50453c2b86417f06649bd452a0c5d6bd2d27e8ee' 
  AND token = 'nZRbkacCZig9ryxCNyTkrA4Wwv6V8CFEdj8iLQ1h7gQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}