SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3af2120d05f0e40e026b67e8112ffdc4f4fe24ea0ae1722c147d1f58b0c208b5' 
  AND token = '+yLICoDW890NLZk14YW2pKVHcPB2PGSdzSbhc4uzxcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}