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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37289beec4d164d9a65d1ebc7eaadb4bdca73091e1730bbc95ed25efe0bfea20' 
  AND token = 'Yp+PrAafTNd/y/hTvwUpJ7z6L5Eh+cxh4r3as1WbRqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}