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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4838ce26d66a59aa860e383a7a927ac04a4a8d66c492aaf92f8a27567ac01af' 
  AND token = 'jp792rMfL6gzUL++cgTPY7WnohMA5ULVDPGra+iithc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}