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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f6b8b5a0162237c85e4b42d782db0026325bb7d4f39c51cba3ecf1ada89fb9' 
  AND token = 'a4X7dFvHqr2Q3ysVX6zBm18SNq+6nAasX+yo88241Ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}