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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b9e6bec464c03c620f70e46d7bc47a264322375dd3e74d7f9bd01da424e4b07' 
  AND token = 'wQ2t1ErZ6wg+q4qnhN2Fmn44yTXx1fB2bkyjCQrpWko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}