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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5646d81b1e4e692e07cd2c6a44535d5b323cc71824abc276c3d9a1ac6e42822' 
  AND token = '23Uv/Tyn/lhAw/0Tc0gvQsC/eEQdKxEtO3xNAp1nR/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}