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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0dd1f6e7edd927b6fb6a3b5de655096f5b5cfc75ad25789c4d399d2361256a2' 
  AND token = 'tiEO6x566oB0bay4UiSQ3MSIDWj1CCfEn1OertKb5kE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}