SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84125e95a717286bd98a96155249ac9ddf4188941ae4e633e905bf6a77b934d5' 
  AND token = 'epc/IiISwMfvxdzX/HFfggnmNlqHTEuLfezgYWUkGKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}