SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e169adf08c65536ed5eaf0cbf1877fa8954d8f61f23936fd0326ec92d57b953' 
  AND token = 'wkAf0h/EjylMSFcWvZpeAbPJzsYtM/Q/6xpMKuPANtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}