SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6b4a1ea5c6621412bf677e67dd22e4f4e1afc3b3ad4d7469265a7d60ac036fb' 
  AND token = '8JXvbe2Ls/dsJihhtyQlEcEuPuAeulJ06EtTqYjm2LQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}