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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '420f0c6e3967ecc498ef93d3830ffc587210d8199f9919419b3d75baa121d769' 
  AND token = 'YyoizvLAS6tgWSKfP6T1oOV8FM3oSX9/ExZrW9YZ/NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}