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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26ae452b25f204d5d989d94d0035298e963685186be5b0ba0c9ffaa7ddf7c251' 
  AND token = '2oMTchHIuDlO2QqiKPCtH3lOoJ3ePGcKquASYWUa9Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}