SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c1a261e1623b7b3adbfea3d0508c816b474dbec35a2970c700605ccfdf6c2d2' 
  AND token = 'Bdh8nY+QUGpVMe2gRP5NXwmca8cgvlqFdtcEl0tJ/wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}