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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb0c88c097871d3acbbe2a513689752a6d1b30a8c37f118107caf19a0c2a68f1' 
  AND token = 't1Gh3caXnLKBxEPDyxdyhhfqFmh/LkcPzC58UOdzlWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}