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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f81161bd08565111e6a0b83d152ea54dfe2181f4a22997810a4f28d8c922d17' 
  AND token = 'Zr7LPyGkxE48r/UWpqfjaV1lijfOn3Xufl8UURtnY9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}